TUESDAY, APRIL 20, 2010, AT 6:19 PM Tornado Kills at Least Five in Oklahoma
FRIDAY, APRIL 29, 2011, AT 3:07 PM Obama Gets Firsthand Look at a Tornado Damage
TUESDAY, APRIL 20, 2010, AT 6:19 PM Tornado Kills at Least Five in Oklahoma. Very long title. Long long long. Tornado Kills at Least Five in Oklahoma. Very long title. Long long long.
TUESDAY, APRIL 20, 2010, AT 6:19 PM Tornado Kills at Least Five in Oklahoma. Very long title. Long long long. Tornado Kills at Least Five in Oklahoma. Very long title. Long long long.
The British artist Banksy is holding a month-long show on the streets of New York. Every day, the reclusive street artist posts a photo of his latest piece and fans locate the piece through social media. But they have to find the art fast — it's often destroyed within hours of being discovered.
Tea Party activists attend a June rally on the grounds of the Capitol.
J. Scott Applewhite/AP
Tea Party activists attend a June rally on the grounds of the Capitol.
J. Scott Applewhite/AP
The Tea Party's standing with Americans is at its lowest point since the movement took shape in 2010, according to a Pew Research Center poll released Wednesday.
The survey, conducted from Oct. 9-13, reports that nearly half (49 percent) of the public now view the Tea Party unfavorably, compared with 30 percent who view it favorably. Since February 2010, when Pew first began gauging opinion on the Tea Party, unfavorable views have nearly doubled, and the number of "very unfavorable" views has tripled.
In June, when Pew last polled on the Tea Party and before the latest Washington budget battle fully ratcheted up, 45 percent said they held an unfavorable view of the Tea Party, while 37 percent reported they had a favorable view.
Michael Dimock, the director of the Pew Research Center for the People and the Press, told All Things Considered host Audie Cornish that one of the issues is that people don't really know what the Tea Party is about.
"There's not really a consensus about what the Tea Party is, whether it's kind of an outside group trying to steer policy or whether it's working within the Republican Party itself," Dimock says.
The poll, which was in the field as congressional Republicans continued their push to remove financing for President Obama's health care law as part of a deal to reopen the government, found that the Tea Party's popularity is falling even among Republicans.
Pew reported that 53 percent of Republicans now view the Tea Party favorably, down from 62 percent in June; and 27 percent view it unfavorably, up from 23 percent in June.
The popularity of freshman Sen. Ted Cruz, R-Texas, who has championed the movement to defund Obamacare, is soaring among Tea Party members: 74 percent view him favorably, while just 8 percent rate him unfavorably.
That's a dramatic rise from July, when 48 percent of Tea Party members said they viewed him favorably. Cruz's stature is also growing among Tea Party Republicans: 18 percent think of him as the leader of the GOP, second only to House Speaker John Boehner, who leads with 28 percent. No other Republican is even close to those two.
But Cruz, a potential 2016 presidential candidate, still has a ways to go in winning over the rest of the GOP.
Thirty-one percent of those classified by Pew as non-Tea Party Republicans view Cruz unfavorably, up from 16 percent in July. Cruz's favorable ratings among those Republicans remained essentially unchanged, and a plurality of non-Tea Party Republicans (44 percent) said they do not have an opinion of Cruz.
Despite the criticism Boehner often receives from the most conservative wing of his party, he continues to have a higher favorability rating among Tea Party members than the rest of the GOP.
Fifty-five percent of Tea Party members hold a favorable opinion of Boehner, a 2-point increase from July, while 35 percent have an unfavorable opinion, up from 28 percent in July. Among non-Tea Party Republicans, 36 percent view Boehner unfavorably, and 35 percent view him favorably.
His GOP counterpart in the Senate, Minority Leader Mitch McConnell, doesn't fare as well with Tea Party members. McConnell, who faces a tough re-election fight in 2014 and is already sustaining attacks from conservative grass-roots groups, saw his unfavorable rating spike over the past three months.
While his favorable rating remained essentially steady among Tea Party members at 45 percent, his unfavorables jumped to 32 percent in October, up from 23 percent in July.
Thirty-three percent of non-Tea Party Republicans also view McConnell unfavorably, an 8-point increase from July.
WInd up your after school specials, the Jenner girls have been out partying again. There have been rumors of the high school dropouts Footloosing with the grownups for some time now, but they’ve managed to mostly hide it from the public eye. But now, last night, not so much. According to paparazzo Blair Hanson on scene:
Kendall and Kylie were leaving a bar called the Wax Rabbit in West Hollywood. The girls jumped into a white Bentley with Scott Disick. The trio looked very sweaty and drunk. Witnesses inside the bar saw the girls taking shots of tequila and drinking Grey Goose vodka. Both girls looked very inebriated and almost passed out in the back of the car.
Apparently, Khloe was also inside the bar polishing off the potato skins while the rest of her wasted family members were ditching her in the Bentley. I’m not going to judge. I experimented with the liquor every now and then or three times a week as a teen. I never got VIP wristbands to hip nightclubs, but tipping doormen with arcade tokens only got you so far. Also, I had to lie to my mom if I wanted to go out on a school night, as opposed to my mom telling me to dress scantily, get loaded, and show off as much ass as possible to the press she was tipping off about my whereabouts. To be a Kardashian, that is the dream.
Everyone has an experience that comes unexpected, such as having to do emergency car maintenance, or pay for urgent doctor’s visits. You may not have the cash in reserve to solve money emergencies, but you can make plans for wise choices for getting you through such times. Do you need assistance? You’ll discover how to effectively weigh the option of obtaining a payday loan through the contents of this article.
You can find a wide variety of payday lenders. Once you have decide to take out a payday loan, you should comparison shop to find a company with good interest rates and reasonable fees. Look specifically for the reaction from customers who chose that company. Just check the Internet to find out about each firm.
Payday Loan
There are many situations where a payday loan is your only option. If there is any way to avoid this type of loan, it is best to do that. Try borrowing money from those around you as a first option, before you consider a payday loan.
Be aware of what a potential payday loan company will charge you prior to getting one. Many borrowers are shocked by how much interest they are charged. Ask the company you plan to use about their interest rates, as well as any fees or penalties that may be charged.
Try taking out loans directly from lenders to get the cheapest rates. By taking an indirect route, you will have to pay more in fees because the lender is paying himself something, too.
Keep your eyes out for businesses that tack on their finance fee to the next pay cycle. The problem is that borrowers tend to just continue paying such charges and the loan never gets fully repaid. People sometimes pay as much as five times the amount of the loan by getting caught in this trap.
Avoid signing an agreement with a lender if you are unclear about anything. If this information is not presented to you clearly, you should see it as a red flag that the company may be a scam.
Payday Loan
Check out different lenders before you decide where to get a payday loan. Some may offer lower rates than others and could also waive fees associated to the loan. One place may be able to fund the loan within an hour, or you may wait for days at another. Seek out the best payday loan company that offers the most benefits to you and your circumstances.
If you require money in a hurry and have no one to turn to, you may want to consider payday advances. You will pay a premium for these loans, but sometimes there is no other option. Remember to use the tips mentioned in the article above in order to safely use cash advances.
What You Need To Know About Dealing With Cash Advance Loans
With layoffs, cutbacks and price increases, people have to make some tough sacrifices. This article can give you become better informed and educated about payday cash advances and their true cost.
Do everything you can to pay the loan by the time it is due.If you extend your loan, you will simply compound the interest and make it even more difficult to pay off the loan down the road.
Take the best rates. There are traditional payday loan businesses located around the city and some online as opposed to an actual store that you physically go into.They want to get your business so they have very competitive in price. Some places will offer a discount to applicants who are borrowing for the first time borrowing. Check all of your options before settling on a lender.
Keep in mind that cash borrowed via a payday loan balances must be repaid fast. You might need to repay your loan in about two weeks or less. The only exceptions are if your next payday lands less than a week after you take out the loan. The associated fees will be lower and you will have to be repaid until the loan.
Indirect loans cost a lot more in fees because they add on fees for themselves.
Watch out for companies that automatically roll over the finance charges to future pay periods. This can cause you to pay a lot more than you initially expected without paying off the actual loan. It isn’t uncommon to pay upwards of five times the loan’s starting value in this way.
Those applying for a payday loan must plan ahead prior to filling out an application. Don’t just jump at the first loan or company you locate.Compare payback policies and interest rates prior to applying to a particular company and choose the terms of different loans before choosing one.
Do not worry if the loan company requests your bank account information. A lot of people back out because they fail to get the loan. The reason cash advance loans is that they can get their money from your account on the due date.
Make sure you are aware of any rollover type payment setups on your account. It may be the case that your lender has a system that automatically renews your unpaid loan and deducts fees are deducted from you banking account. Know and understand what you are getting into.
Be sure you know the amount your payday loan will cost you. It’s common knowledge that rates for payday loan providers charge extremely high interest rates. They may also tack on administration fees for taking out a loan. The administrative fees you might incur can be hidden in the contract’s fine print.
If you have taken out more than one payday loan at at time and are having trouble paying them off, you should not attempt to consolidate them.
If you are in need of fast cash and have nowhere else to turn, a payday loan may be a good choice for you – as long as you are gainfully employed and have your check direct deposited. Payday cash advances come with substantial interest rates, but do offer you help in occasional emergencies. Keep the information you learned in mind to help you make smart choices with payday advances.
Contact: Dr. Stefanie Merker merker@neuro.mpg.de 49-898-578-3514 Max-Planck-Gesellschaft
Neurons strengthen their synapses in order to remain active after loss of input
This news release is available in German.
The brain is an extremely adaptable organ but it is also quite conservative. That's in short, what scientists from the Max Planck Institute of Neurobiology in Martinsried and their colleagues from the Friedrich Miescher Institute in Basel and the Ruhr-Universitt Bochum were now able to show. The researchers found that neurons in the brain regulate their own activity in such a way that the overall activity level in the network remains as constant as possible. This remains true even in the event of major changes: After the complete loss of information from a sensory organ, for example, the almost silenced neurons re-establish levels of activity similar to their previous ones after only 48 hours. The mean activity level thus achieved is a basic prerequisite for a healthy brain and the formation of new connections between neurons an essential capacity for regeneration following injury to the brain or a sensory organ, for example.
Neurons communicate using electrical signals. They transmit these signals to neighbouring cells via special contact points known as synapses. When new information needs processing, the nerve cells can develop new synaptic contacts with their neighbouring cells or strengthen existing synapses. To be able to forget, these processes can also be reversed. The brain is consequently in a constant state of reorganisation, yet individual neurons need to be prevented from becoming either too active or too inactive. The aim is to keep the level of activity constant, as the long-term overexcitement of neurons can result in damage to the brain.
Too little activity is not good either. "The cells can only re-establish connections with their neighbours when they are 'awake', so to speak, that is when they display a minimum level of activity", explains Mark Hbener, head of the recently published study. The international team of researchers succeeded in demonstrating for the first time that the brain is able to compensate even massive changes in neuronal activity within a period of two days, and can return to an activity level similar to that before the change.
Up to now, only cell cultures gave an indication of this astonishing ability of the brain. It was also unclear as to how neurons could control their own activity in relation to the activity of the entire network. Now, the scientists have made significant progress towards finding an answer to this question. In their study, they examined the visual cortex of mice that recently went blind. As expected, but never previously demonstrated, the activity of the neurons in this area of the brain did not fall to zero but to half of the original value. "That alone was an amazing finding, as it shows the extent to which the visual cortex also processes information from other areas of the brain," explains Tobias Bonhoeffer, who investigates processes in the visual cortex with his department at the Max Planck Institute of Neurobiology for many years. "However, things became really exciting when we continued to observe the area over the following hours and days."
The scientists were able to witness "live" through the microscope how the neurons in the visual cortex became active again. After just a few hours, they could clearly observe how the contact points between the affected neurons and their neighbouring cells increased in size. When synapses get bigger, they also become stronger and signals are transmitted faster and more effectively. As a result of this synaptic upscaling, the activity of the affected network returned to its starting value after a period of between 24 and 48 hours. "To put it simply, due to the absence of visual input, the cells had less to say but when they did say something, they said it with particular emphasis," explains Mark Hbener.
Due to the simultaneous strengthening of all of the synapses of the affected neurons, major reductions in the neuronal activity can be normalised again with surprising speed. The relatively stable activity level thereby achieved is an essential prerequisite for maintaining a healthy, adaptable brain.
###
Original publication:
Tara Keck, Georg B. Keller, R. Irene Jacobsen, Ulf T. Eysel, Tobias Bonhoeffer, Mark Hbener
Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo
Neuron, 16 October 2013
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When neurons have less to say, they speak up
Public release date: 16-Oct-2013 [
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Contact: Dr. Stefanie Merker merker@neuro.mpg.de 49-898-578-3514 Max-Planck-Gesellschaft
Neurons strengthen their synapses in order to remain active after loss of input
This news release is available in German.
The brain is an extremely adaptable organ but it is also quite conservative. That's in short, what scientists from the Max Planck Institute of Neurobiology in Martinsried and their colleagues from the Friedrich Miescher Institute in Basel and the Ruhr-Universitt Bochum were now able to show. The researchers found that neurons in the brain regulate their own activity in such a way that the overall activity level in the network remains as constant as possible. This remains true even in the event of major changes: After the complete loss of information from a sensory organ, for example, the almost silenced neurons re-establish levels of activity similar to their previous ones after only 48 hours. The mean activity level thus achieved is a basic prerequisite for a healthy brain and the formation of new connections between neurons an essential capacity for regeneration following injury to the brain or a sensory organ, for example.
Neurons communicate using electrical signals. They transmit these signals to neighbouring cells via special contact points known as synapses. When new information needs processing, the nerve cells can develop new synaptic contacts with their neighbouring cells or strengthen existing synapses. To be able to forget, these processes can also be reversed. The brain is consequently in a constant state of reorganisation, yet individual neurons need to be prevented from becoming either too active or too inactive. The aim is to keep the level of activity constant, as the long-term overexcitement of neurons can result in damage to the brain.
Too little activity is not good either. "The cells can only re-establish connections with their neighbours when they are 'awake', so to speak, that is when they display a minimum level of activity", explains Mark Hbener, head of the recently published study. The international team of researchers succeeded in demonstrating for the first time that the brain is able to compensate even massive changes in neuronal activity within a period of two days, and can return to an activity level similar to that before the change.
Up to now, only cell cultures gave an indication of this astonishing ability of the brain. It was also unclear as to how neurons could control their own activity in relation to the activity of the entire network. Now, the scientists have made significant progress towards finding an answer to this question. In their study, they examined the visual cortex of mice that recently went blind. As expected, but never previously demonstrated, the activity of the neurons in this area of the brain did not fall to zero but to half of the original value. "That alone was an amazing finding, as it shows the extent to which the visual cortex also processes information from other areas of the brain," explains Tobias Bonhoeffer, who investigates processes in the visual cortex with his department at the Max Planck Institute of Neurobiology for many years. "However, things became really exciting when we continued to observe the area over the following hours and days."
The scientists were able to witness "live" through the microscope how the neurons in the visual cortex became active again. After just a few hours, they could clearly observe how the contact points between the affected neurons and their neighbouring cells increased in size. When synapses get bigger, they also become stronger and signals are transmitted faster and more effectively. As a result of this synaptic upscaling, the activity of the affected network returned to its starting value after a period of between 24 and 48 hours. "To put it simply, due to the absence of visual input, the cells had less to say but when they did say something, they said it with particular emphasis," explains Mark Hbener.
Due to the simultaneous strengthening of all of the synapses of the affected neurons, major reductions in the neuronal activity can be normalised again with surprising speed. The relatively stable activity level thereby achieved is an essential prerequisite for maintaining a healthy, adaptable brain.
###
Original publication:
Tara Keck, Georg B. Keller, R. Irene Jacobsen, Ulf T. Eysel, Tobias Bonhoeffer, Mark Hbener
Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo
Neuron, 16 October 2013
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| E-mail
| Share
]
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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